PNMT Rabbit Polyclonal Antibody (CAB5553)
- SKU:
- CAB5553
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PNMT Rabbit Polyclonal Antibody |
SKU: | CAB5553 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human PNMT (NP_002677.1). |
Sequence: | MSGA DRSP NAGA APDS APGQ AAVA SAYQ RFEP RAYL RNNY APPR GDLC NPNG VGPW KLRC LAQT FATG EVSG RTLI DIGS GPTV YQLL SACS HFED ITMT DFLE VNRQ ELGR WLQE EPGA FNWS MYSQ HACL IEGK GECW QDKE RQLR ARVK RVLP IDVH QPQP LGAG SPAP LPAD ALVS AFCL EAVS PDLA SFQR ALDH ITTL LRPG GHLL LIGA LEES WYLA GEAR LTVV PVSE EEVR EALV RSGY KVRD LRTY IMPA HLQT GVDD VKGV FFAW AQKV GL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PENT; PNMTase; PNMT |
Positive Sample: | K-562,Mouse liver,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 31kDa |
Observed MW: | 31-34kDa |
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5409 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |