The PNMA1 Polyclonal Antibody (CAB14558) offered by AssayGenie is a valuable tool for research involving the PNMA1 protein, which is known to be associated with paraneoplastic neurological syndrome. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding specifically to the PNMA1 protein, researchers can detect and analyze this important molecule in various cell types, making it ideal for studies in neurology and cancer research.
PNMA1, also known as Paraneoplastic Ma Antigen 1, is a protein that is believed to play a role in the development and progression of paraneoplastic neurological disorders. Understanding the function and regulation of PNMA1 is crucial for advancing our knowledge of these conditions and potentially developing new treatments. This antibody provides a reliable tool for investigating the role of PNMA1 in disease processes and may lead to important discoveries in the field of neurology and oncology.
Product Name:
PNMA1 Rabbit Polyclonal Antibody
SKU:
CAB14558
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human PNMA1 (NP_006020.4).
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors.
Purification Method:
Affinity purification
Gene ID:
9240
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PNMA1 Rabbit pAb (CAB14558) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
