The PNLIP Polyclonal Antibody (CAB7421) is a valuable tool for research involving Pancreatic Lipase (PNLIP), an enzyme responsible for the digestion of dietary fats in the small intestine. This antibody, produced in rabbits, has high specificity and sensitivity for detecting PNLIP in human samples, making it an ideal choice for Western blot applications. PNLIP plays a crucial role in lipid digestion and absorption, making it an important target for studies related to digestive health, obesity, and metabolic disorders.
By detecting and analyzing PNLIP expression in various cell types, researchers can gain insights into its function and potential therapeutic implications.The PNLIP Polyclonal Antibody is a reliable tool for investigating the role of PNLIP in lipid metabolism and related diseases, providing valuable information for the development of treatments and interventions aimed at improving digestive health and metabolic function.
Product Name:
PNLIP Rabbit Polyclonal Antibody
SKU:
CAB7421
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 166-465 of human PNLIP (NP_000927.1).
This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.
Purification Method:
Affinity purification
Gene ID:
5406
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from BxPC-3 cells, using PNLIP Rabbit pAb (CAB7421) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 15s.
