The PNPLA Polyclonal Antibody (CAB17838) is a powerful tool for researchers studying PNPLA, a key enzyme involved in lipid metabolism and energy homeostasis. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for use in Western blotting and immunofluorescence applications. By binding to the PNPLA protein, this antibody allows for the detection and analysis of PNPLA in a variety of cell types, providing valuable insights into its function in metabolic pathways and potential implications for diseases such as obesity, diabetes, and fatty liver disease.
PNPLA, also known as patatin-like phospholipase domain-containing protein, is essential for the breakdown of triglycerides and the regulation of lipid storage in cells. Dysregulation of PNPLA activity has been linked to metabolic disorders and cardiovascular diseases, making it a promising target for therapeutic interventions aimed at improving metabolic health. By studying the function of PNPLA using this antibody, researchers can further our understanding of lipid metabolism and potentially identify new strategies for treating metabolic disorders.
Product Name:
PNLDC1 Rabbit Polyclonal Antibody
SKU:
CAB17838
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human PNLDC1 (NP_775787.1).
Enables poly(A)-specific ribonuclease activity. Involved in nuclear-transcribed mRNA poly(A) tail shortening. Located in endoplasmic reticulum. Implicated in spermatogenic failure.
Purification Method:
Affinity purification
Gene ID:
154197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PNLDC1 Rabbit pAb (CAB17838) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
