Description
PNCK Antibody (PACO11324)
The PNCK Polyclonal Antibody (PAC011324) is a valuable tool for researchers studying the PNCK protein, a kinase involved in cellular signaling pathways. The antibody is produced in rabbits and is highly specific for detecting PNCK in human samples. Validated for use in Western blot applications, this antibody enables accurate detection and analysis of PNCK in a variety of cell types, making it essential for studies in cell signaling and cancer research.PNCK is known for its role in regulating cellular processes such as cell proliferation, differentiation, and survival.
Its dysregulation has been associated with various diseases, including cancer and neurological disorders. By understanding the function of PNCK, researchers can gain valuable insights into the underlying mechanisms of these conditions and potentially develop targeted therapies to treat them.Overall, the PNCK Polyclonal Antibody is a reliable tool for investigating the function of PNCK in a research context, providing essential information for advancing our understanding of cellular signaling pathways and disease mechanisms.
Antibody Name: | PNCK Antibody (PACO11324) |
Antibody SKU: | PACO11324 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human PNCK |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | pregnancy up-regulated non-ubiquitously expressed CaM kinase;PNCK;BSTK3;CaMK1b;FLJ50403;FLJ50549;FLJ56451;FLJ59811;MGC45419 ; |
UniProt Protein Function: | CAMK1B: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.17; CAMK group; CAMK1 family Chromosomal Location of Human Ortholog: Xq28 |
NCBI Summary: | PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6P2M8 |
NCBI GenInfo Identifier: | 67466915 |
NCBI Gene ID: | 139728 |
NCBI Accession: | Q6P2M8.2 |
UniProt Secondary Accession: | Q6P2M8,Q8N4R0, B4DJR8, B4E1A6, B7WPG0, D3DWU7, |
UniProt Related Accession: | Q6P2M8 |
Molecular Weight: | 40,356 Da |
NCBI Full Name: | Calcium/calmodulin-dependent protein kinase type 1B |
NCBI Synonym Full Names: | pregnancy up-regulated nonubiquitous CaM kinase |
NCBI Official Symbol: | PNCKÂ Â |
NCBI Official Synonym Symbols: | BSTK3; CaMK1b  |
NCBI Protein Information: | calcium/calmodulin-dependent protein kinase type 1B |
UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase type 1B |
UniProt Synonym Protein Names: | CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase |
Protein Family: | Calcium/calmodulin-dependent protein kinase |
UniProt Gene Name: | PNCKÂ Â |
UniProt Entry Name: | KCC1B_HUMAN |