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PNCK Antibody (PACO03503)

SKU:
PACO03503
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269

Description

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PNCK Antibody (PACO03503)

The PNCK Polyclonal Antibody (PAC003503) is a vital tool for researchers studying PNCK, a protein kinase involved in various cellular processes such as cell signaling and proliferation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the PNCK protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an ideal choice for studies in cell biology and cancer research.PNCK, a member of the protein kinase C (PKC) family, is known to play a pivotal role in regulating cellular functions such as cell growth and differentiation.

Its involvement in key signaling pathways makes it a promising target for research aimed at understanding diseases like cancer, where abnormal cell proliferation and signaling are common features. By elucidating the role of PNCK in disease pathology, researchers can uncover new therapeutic strategies that target this kinase for potential treatment options.

Antibody Name:PNCK Antibody
Antibody SKU:PACO03503
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the Internal region of human CaMKIBeta.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:PNCK; Calcium/calmodulin-dependent protein kinase type 1B; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
UniProt Protein Function:CAMK1B: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.17; CAMK group; CAMK1 family

Chromosomal Location of Human Ortholog: Xq28

NCBI Summary:PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008]
UniProt Code:Q6P2M8
NCBI GenInfo Identifier:67466915
NCBI Gene ID:139728
NCBI Accession:Q6P2M8.2
UniProt Secondary Accession:Q6P2M8,Q8N4R0, B4DJR8, B4E1A6, B7WPG0, D3DWU7,
UniProt Related Accession:Q6P2M8
Molecular Weight:40,356 Da
NCBI Full Name:Calcium/calmodulin-dependent protein kinase type 1B
NCBI Synonym Full Names:pregnancy up-regulated nonubiquitous CaM kinase
NCBI Official Symbol:PNCK  
NCBI Official Synonym Symbols:BSTK3; CaMK1b  
NCBI Protein Information:calcium/calmodulin-dependent protein kinase type 1B
UniProt Protein Name:Calcium/calmodulin-dependent protein kinase type 1B
UniProt Synonym Protein Names:CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
Protein Family:Calcium/calmodulin-dependent protein kinase
UniProt Gene Name:PNCK  
UniProt Entry Name:KCC1B_HUMAN

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