PMS1 Rabbit Polyclonal Antibody (CAB14046)
- SKU:
- CAB14046
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PMS1 Rabbit Polyclonal Antibody |
SKU: | CAB14046 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1 (NP_000525.1). |
Sequence: | DCLN HQIS IGDF GYGH CSSE ISNI DKNT KNAF QDIS MSNV SWEN SQTE YSKT CFIS SVKH TQSE NGNK DHID ESGE NEEE AGLE NSSE ISAD EWSR GNIL KNSV GENI EPVK ILVP EKSL PCKV SNNN YPIP EQMN LNED SCNK KSNV IDNK SGKV TAYD LLSN RVIK KPMS ASAL FVQD HRPQ FLIE NPKT SLED ATLQ IEEL WKTL SEEE KLK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MLH2; PMSL1; hPMS1; HNPCC3; PMS1 |
Positive Sample: | Mouse liver,Mouse spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 106kDa |
Observed MW: | 110kDa |
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Purification Method: | Affinity purification |
Gene ID: | 5378 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |