The PMPCB Polyclonal Antibody (CAB12549) is a valuable tool for researchers studying PMPCB, a protein involved in cellular metabolism and mitochondrial function. This antibody, produced using rabbit immunization, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the PMPCB protein, this antibody allows for accurate detection and analysis in various cell types, making it ideal for investigations in biochemistry and molecular biology.PMPCB, also known as peroxisomal membrane protein PMP70, plays a crucial role in lipid metabolism and the transport of fatty acids into peroxisomes.
Dysregulation of PMPCB has been linked to metabolic disorders and diseases related to peroxisomal dysfunction. Research on PMPCB is essential for understanding its role in these conditions and developing targeted therapies. By utilizing the PMPCB Polyclonal Antibody, researchers can further explore the functions of PMPCB in health and disease, advancing our knowledge of cellular metabolism and potentially uncovering new treatment strategies.
Product Name:
PMPCB Rabbit Polyclonal Antibody
SKU:
CAB12549
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-380 of human PMPCB (NP_004270.2).
This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
Purification Method:
Affinity purification
Gene ID:
9512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PMPCB antibody (CAB12549) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
