The PMPCA Polyclonal Antibody (CAB9965) is an essential tool for researchers studying the PMPCA protein, a key player in cellular metabolism and energy production. This antibody, produced in rabbits, is highly specific for detecting PMPCA in human samples and is validated for use in Western blot applications.PMPCA, also known as Phosphorylated Multifunctional Protein Complex A, is involved in the regulation of various metabolic pathways, making it a promising target for understanding metabolic disorders, such as diabetes and obesity. By using this antibody, researchers can accurately detect and analyze PMPCA levels in different cell types, aiding in the study of metabolic diseases and potential therapeutic interventions.
With its high reactivity and specificity, the PMPCA Polyclonal Antibody is a valuable tool for researchers in the fields of metabolism, biochemistry, and cell biology. Its ability to accurately detect PMPCA protein expression makes it an essential component in studies aiming to unravel the complex mechanisms underlying metabolic disorders and explore new treatment options.
Product Name:
PMPCA Rabbit Polyclonal Antibody
SKU:
CAB9965
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 456-525 of human PMPCA (NP_055975.1).
The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.
Purification Method:
Affinity purification
Gene ID:
23203
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PMPCA antibody (CAB9965) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.