PMM2 Rabbit Polyclonal Antibody (CAB4026)
- SKU:
- CAB4026
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PMM2 Rabbit Polyclonal Antibody |
SKU: | CAB4026 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PMM2 (NP_000294.1). |
Sequence: | MAAP GPAL CLFD VDGT LTAP RQKI TKEM DDFL QKLR QKIK IGVV GGSD FEKV QEQL GNDV VEKY DYVF PENG LVAY KDGK LLCR QNIQ SHLG EALI QDLI NYCL SYIA KIKL PKKR GTFI EFRN GMLN VSPI GRSC SQEE RIEF YELD KKEN IRQK FVAD LRKE FAGK GLTF SIGG QISF DVFP DGWD KRYC LRHV ENDG YKTI YFFG DKTM PGGN DHEI FTDP RTMG YSVT APED TRRI CELL FS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PMI; CDG1; CDGS; PMI1; CDG1a; PMM 2; PMM2 |
Positive Sample: | HepG2,A-549,HeLa,293T,NIH/3T3,Mouse liver,Mouse intestine,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
Purification Method: | Affinity purification |
Gene ID: | 5373 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |