The PMEPA1 Polyclonal Antibody (CAB16555) is a valuable tool for researchers studying PMEPA1, a protein involved in various cellular processes including cell growth and differentiation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the PMEPA1 protein, this antibody allows for the detection and analysis of PMEPA1 expression in different cell types, making it suitable for investigations in the fields of cancer biology and cell signaling pathways.
PMEPA1, also known as prostate transmembrane protein, has been implicated in the regulation of cell proliferation and apoptosis, making it a potential target for therapeutic interventions in cancer and other diseases. By understanding the role of PMEPA1 in cellular functions, researchers can develop novel strategies for combating cancer progression and other related disorders. The PMEPA1 Polyclonal Antibody is a valuable asset for studies aiming to unravel the complexities of PMEPA1 signaling pathways and its impact on disease mechanisms.
Product Name:
PMEPA1 Rabbit Polyclonal Antibody
SKU:
CAB16555
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 173-252 of human PMEPA1 (NP_954638.1).
Early endosome membrane, Golgi apparatus membrane, Single-pass membrane protein.
Calculated MW:
32kDa
Observed MW:
Refer to figures
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
56937
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat ovary using PMEPA1 Rabbit pAb (CAB16555) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
