The PLZF Monoclonal Antibody is a specialized antibody designed for research involving the PLZF protein, also known as Promyelocytic Leukemia Zinc Finger. PLZF is a transcription factor that plays a key role in regulating gene expression and is implicated in various biological processes, including cell differentiation and development.This monoclonal antibody, produced using hybridoma technology, is highly specific for PLZF and has been validated for use in immunohistochemistry, flow cytometry, and other experimental techniques. Its ability to target PLZF enables precise detection and analysis of this important protein in a variety of cell types and tissues, making it an invaluable tool for researchers in the fields of stem cell biology, oncology, and developmental biology.
By studying PLZF and its functions, researchers can gain valuable insights into its role in normal physiological processes as well as its potential involvement in diseases such as cancer, leukemia, and other disorders. The PLZF Monoclonal Antibody offers a reliable solution for investigating the complex functions of PLZF and exploring its therapeutic potential in various medical conditions.
Product Name:
PLZF Monoclonal Antibody
SKU:
CAB21185
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 199-300 of human PLZF (NP_005997.2).
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
Purification Method:
Affinity purification
Gene ID:
7704
Clone Number:
ARC52265
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLZF Rabbit mAb (CAB21185) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
