The PLXNB3 Polyclonal Antibody (CAB16064) is specially designed for research involving PLXNB3, a member of the plexin family of proteins that plays a crucial role in cell migration and axon guidance in the nervous system. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the PLXNB3 protein, this antibody enables the detection and analysis of PLXNB3 expression in various cell types, making it an ideal tool for studies in neuroscience and developmental biology.PLXNB3, also known as plexin B3, is involved in mediating signaling pathways that control cellular behavior, such as cell adhesion and cytoskeletal dynamics.
Its role in axon guidance and neural development makes it a key player in processes like neuronal migration and axon growth. Research into PLXNB3 function is important for understanding neurodevelopmental disorders, neurodegenerative diseases, and other conditions related to nervous system dysfunction. By elucidating the mechanisms by which PLXNB3 operates, scientists can uncover potential targets for therapeutic interventions aimed at treating neurological disorders.
Product Name:
PLXNB3 Rabbit Polyclonal Antibody
SKU:
CAB16064
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1050-1250 of human PLXNB3 (NP_001156729.1).
Cell membrane, Single-pass type I membrane protein
Calculated MW:
207kDa
Observed MW:
170kDa
The protein encoded by this gene is a member of the plexin family. It functions as a receptor for semaphorin 5A, and plays a role in axon guidance, invasive growth and cell migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5365
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using PLXNB3 Rabbit pAb (CAB16064) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
