The PLXNA3 Polyclonal Antibody (CAB14908) is a valuable tool for researchers studying PLXNA3, a cell surface receptor involved in axon guidance and cell migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in applications such as Western blotting.PLXNA3 is a member of the plexin family of proteins, known for their role in mediating cell signaling pathways involved in neuronal development and cancer progression. As such, understanding the function of PLXNA3 is essential for investigating its potential implications in neurological disorders and cancer metastasis.
By targeting the PLXNA3 protein, this antibody enables researchers to detect and analyze its expression levels in various cells and tissues, making it an invaluable tool for studies in neuroscience and oncology. Its high specificity and sensitivity make it suitable for use in both basic research and clinical applications, providing valuable insights into the role of PLXNA3 in health and disease.
Product Name:
PLXNA3 Rabbit Polyclonal Antibody
SKU:
CAB14908
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human PLXNA3 (NP_059984.3).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
208kDa
Observed MW:
208kDa
This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression.
Purification Method:
Affinity purification
Gene ID:
55558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse skeletal muscle, using PLXNA3 Rabbit pAb (CAB14908) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
