The PLXNA3 Polyclonal Antibody (CAB14907) is an essential tool for researchers studying PLXNA3, a protein involved in axon guidance and cell migration. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the PLXNA3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in developmental biology and neurology.PLXNA3 is a key player in the intricate process of axon guidance, directing the growth of nerve cells during development and regeneration. Its role in cell migration also makes it a crucial factor in cancer metastasis and neurological disorders.
Investigating the function of PLXNA3 can provide valuable insights into the mechanisms underlying these conditions, potentially leading to the development of targeted therapies.Overall, the PLXNA3 Polyclonal Antibody is an invaluable tool for researchers seeking to deepen their understanding of PLXNA3 and its biological significance. By enabling accurate detection and analysis of this protein, this antibody paves the way for groundbreaking discoveries in the fields of developmental biology, neurology, and cancer research.
Product Name:
PLXNA3 Rabbit Polyclonal Antibody
SKU:
CAB14907
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human PLXNA3 (NP_059984.3).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
208kDa
Observed MW:
208kDa
This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression.
Purification Method:
Affinity purification
Gene ID:
55558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using PLXNA3 Rabbit pAb (CAB14907) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
