The PLXDC1 Antibody (PAC021891) is a polyclonal antibody designed for research involving PLXDC1, a transmembrane protein involved in cell adhesion and extracellular matrix interaction. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry.PLXDC1, also known as Plexin domain-containing protein 1, plays a critical role in angiogenesis and tumor growth by facilitating cell migration and invasion. Its overexpression has been linked to poor prognosis in cancer patients, making it a potential target for therapeutic intervention.
Research into PLXDC1 can provide insights into tumor progression and identify potential strategies for cancer treatment.This antibody enables specific detection and analysis of PLXDC1 protein expression in different cell types, making it a valuable tool for researchers studying cancer biology, tumor development, and angiogenesis. Understanding the role of PLXDC1 in these processes is essential for the development of targeted therapies and the advancement of precision medicine in oncology.
Antibody Name:
PLXDC1 Antibody (PACO21891)
Antibody SKU:
PACO21891
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from Internal of human PLXDC1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Nanda A., Cancer Res. 64:8507-8511(2004)
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Immunohistochemical analysis of paraffin-embedded human brain tissue using PLXDC1 antibody.
PLXDC1: Plays a critical role in endothelial cell capillary morphogenesis. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Cell surface; Membrane protein, integralChromosomal Location of Human Ortholog: 17q21.1Cellular Component: receptor complexMolecular Function: protein binding
