The PLXDC1 Polyclonal Antibody (PAC004795) is a valuable tool for researchers studying PLXDC1, a transmembrane protein involved in cell adhesion and migration. This antibody, generated in rabbits, is highly specific for human PLXDC1 and has been validated for use in Western blot applications. It binds to the PLXDC1 protein, allowing for accurate detection and analysis in a variety of cell types, making it well-suited for investigations in cancer biology and developmental biology.PLXDC1, also known as plexin domain-containing protein 1, plays a crucial role in cell signaling and interaction with extracellular matrix proteins, influencing processes such as cell migration and adhesion.
Its involvement in these fundamental cellular processes makes it a key target for research in cancer metastasis, angiogenesis, and tissue development. By understanding the function of PLXDC1, researchers can gain insights into how alterations in its activity may contribute to disease progression and potential therapeutic strategies.
Antibody Name:
PLXDC1 Antibody
Antibody SKU:
PACO04795
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human TEM7.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
PLXDC1: Plays a critical role in endothelial cell capillary morphogenesis. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Cell surface; Membrane protein, integralChromosomal Location of Human Ortholog: 17q21.1Cellular Component: receptor complexMolecular Function: protein binding