The PLTP Polyclonal Antibody (CAB5628) is a crucial tool for research involving PLTP, a protein involved in lipid metabolism and cardiovascular health. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the PLTP protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies related to lipid metabolism, atherosclerosis, and cardiovascular diseases.PLTP, also known as phospholipid transfer protein, plays a key role in lipid transport and metabolism, specifically in the transfer of phospholipids between lipoproteins.
Dysregulation of PLTP has been linked to abnormalities in lipid profiles and increased risk of cardiovascular diseases such as atherosclerosis. Therefore, research on the function of PLTP is essential for understanding the mechanisms underlying these conditions and developing targeted therapeutic interventions.By utilizing the PLTP Polyclonal Antibody (CAB5628), researchers can gain valuable insights into the role of PLTP in lipid metabolism and cardiovascular health, paving the way for new advancements in the prevention and treatment of cardiovascular diseases.
Product Name:
PLTP Rabbit Polyclonal Antibody
SKU:
CAB5628
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 142-441 of human PLTP (NP_872617.1).
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5360
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PLTP antibody (CAB5628) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
