The PLSCR3 Polyclonal Antibody (CAB12371) is a valuable tool for researchers studying the phospholipid scramblase 3 (PLSCR3) protein. PLSCR3 is involved in phospholipid translocation and cell membrane dynamics, playing a crucial role in various cellular processes such as apoptosis, cell signaling, and lipid metabolism.This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for use in a variety of applications including Western blotting, immunofluorescence, and immunohistochemistry. By binding to the PLSCR3 protein, this antibody enables researchers to detect and analyze the expression levels and localization of PLSCR3 in different cell types and tissues.
The study of PLSCR3 is important in understanding its role in cellular functions and its potential implications in diseases such as cancer, cardiovascular disorders, and neurological conditions. By investigating the function and regulation of PLSCR3, researchers can gain valuable insights into its involvement in disease pathology and may uncover new therapeutic targets for intervention.
Product Name:
PLSCR3 Rabbit Polyclonal Antibody
SKU:
CAB12371
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human PLSCR3 (NP_065093.2).
Mitochondrion membrane, Single-pass type II membrane protein.
Calculated MW:
32kDa
Observed MW:
32kDa
Enables several functions, including calcium-dependent protein binding activity; metal ion binding activity; and phospholipid scramblase activity. Involved in several processes, including cardiolipin biosynthetic process; regulation of apoptotic process; and regulation of release of cytochrome c from mitochondria. Located in cytosol; mitochondrion; and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
57048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLSCR3 Rabbit pAb (CAB12371) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.