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Phospholipid Scramblase 1 (PLSCR1) Rabbit Monoclonal Antibody (CAB3430)

SKU:
CAB3430
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MMTRA1B
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospholipid Scramblase 1 (PLSCR1) Rabbit Monoclonal Antibody
SKU:CAB3430
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Phospholipid Scramblase 1 (PLSCR1) (NP_066928.1).
Sequence:MDKQ NSQM NASH PETN LPVG YPPQ YPPT AFQG PPGY SGYP GPQV SYPP PPAG HSGP GPAG FPVP NQPV YNQP VYNQ PVGA AGVP WMPA PQPP LNCP PGLE
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:MMTRA1B; Phospholipid Scramblase 1 (PLSCR1)
Positive Sample:HT-29, Mouse lung
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Nucleus, Cytoplasm, Cytoplasm, perinuclear region
Calculated MW:35kDa
Observed MW:35kDa

This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses.

Purification Method:Affinity purification
Gene ID:5359
Clone Number:ARC2028
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HT-29 cells, using Phospholipid Phospholipid Scramblase 1 (PLSCR1) (PLSCR1) Rabbit mAb (CAB3430) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

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