The PLP2 Polyclonal Antibody (PAC011307) is a valuable tool for researchers studying PLP2, a protein involved in regulating immune response and inflammation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the PLP2 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for immunology and cancer research studies.PLP2, also known as immune regulatory protein, plays a key role in immune system modulation by controlling inflammatory responses and regulating immune cell activity.
Its involvement in immune regulation highlights its importance as a target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of PLP2 is crucial for developing targeted therapies that manipulate immune responses for therapeutic benefit.
proteolipid protein 2 (colonic epithelium-enriched);PLP2;A4;A4-LSB;MGC126187 ;
UniProt Protein Function:
PLP2: May play a role in cell differentiation in the intestinal epithelium. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Endoplasmic reticulum; Membrane protein, integral; Cell development/differentiation; Membrane protein, multi-passChromosomal Location of Human Ortholog: Xp11.23Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane; plasma membraneMolecular Function: chemokine binding; ion transmembrane transporter activity; protein bindingBiological Process: ion transport
UniProt Protein Details:
NCBI Summary:
This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]
