PLP1 Rabbit Polyclonal Antibody (CAB20009)
- SKU:
- CAB20009
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | PLP1 Rabbit Polyclonal Antibody |
SKU: | CAB20009 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-150 of human PLP1 (NP_000524.3). |
Sequence: | GFYT TGAV RQIF GDYK TTIC GKGL SATV TGGQ KGRG SRGQ HQAH SLER VCHC LGKW LGHP D |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20; PLP1 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein, Myelin membrane. |
Calculated MW: | 30kDa |
Observed MW: | 20-25kDa |
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
Purification Method: | Affinity purification |
Gene ID: | 5354 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |