PLOD3 Rabbit Polyclonal Antibody (CAB10547)
- SKU:
- CAB10547
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PLOD3 Rabbit Polyclonal Antibody |
SKU: | CAB10547 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human PLOD3 (NP_001075.1). |
Sequence: | SDRP RGRD PVNP EKLL VITV ATAE TEGY LRFL RSAE FFNY TVRT LGLG EEWR GGDV ARTV GGGQ KVRW LKKE MEKY ADRE DMII MFVD SYDV ILAG SPTE LLKK FVQS GSRL LFSA ESFC WPEW GLAE QYPE VGTG KRFL NSGG FIGF ATTI HQIV RQWK YKDD DDDQ LFYT RLYL DPGL REKL SLNL DHKS RIFQ NLNG ALDE VVLK FDRN RVRI RNVA YDTL PIVV HGNG PTKL QLNY LGNY VPNG WTPE GGCG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | LH3; PLOD3 |
Positive Sample: | HepG2,BxPC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Lumenal side, Peripheral membrane protein, Rough endoplasmic reticulum membrane. |
Calculated MW: | 85kDa |
Observed MW: | 85kDa |
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
Purification Method: | Affinity purification |
Gene ID: | 8985 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |