PLOD1 Rabbit Polyclonal Antibody (CAB14044)
- SKU:
- CAB14044
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PLOD1 Rabbit Polyclonal Antibody |
SKU: | CAB14044 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2). |
Sequence: | RQQD VFMF LTNR HTLG HLLS LDSY RTTH LHND LWEV FSNP EDWK EKYI HQNY TKAL AGKL VETP CPDV YWFP IFTE VACD ELVE EMEH FGQW SLGN NKDN RIQG GYEN VPTI DIHM NQIG FERE WHKF LLEY IAPM TEKL YPGY YTRA QFDL AFVV RYKP DEQP SLMP HHDA STFT INIA LNRV GVDY EGGG CRFL RYNC SIRA PRKG WTLM HPGR LTHY HEGL PTTR GTRY IAVS FVDP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LH; LH1; LLH; EDS6; PLOD; EDSKCL1; PLOD1 |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Lumenal side, Peripheral membrane protein, Rough endoplasmic reticulum membrane. |
Calculated MW: | 84kDa |
Observed MW: | 125kDa |
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5351 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |