The PLK2 Polyclonal Antibody (CAB7066) is a valuable tool for researchers studying PLK2, a protein kinase involved in cell cycle regulation and neuronal function. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PLK2 protein, researchers can accurately detect and analyze its expression in a variety of cell types.PLK2, also known as polo-like kinase 2, plays a crucial role in cell division and DNA damage response, making it a key target for studies in cancer research and neurobiology.
Its dysregulation has been implicated in various diseases, including Alzheimer's and Parkinson's, highlighting the importance of understanding its function. By utilizing the PLK2 Polyclonal Antibody, researchers can further investigate the role of this kinase in disease pathology and potential therapeutic interventions.
Product Name:
PLK2 Rabbit Polyclonal Antibody
SKU:
CAB7066
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 361-439 of human PLK2 (NP_006613.2).
The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10769
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PLK2 antibody (CAB7066) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
