PLK1 Rabbit Polyclonal Antibody (CAB2548)
- SKU:
- CAB2548
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | PLK1 Rabbit Polyclonal Antibody |
SKU: | CAB2548 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 304-603 of human PLK1 (NP_005021.2). |
Sequence: | FFTS GYIP ARLP ITCL TIPP RFSI APSS LDPS NRKP LTVL NKGL ENPL PERP REKE EPVV RETG EVVD CHLS DMLQ QLHS VNAS KPSE RGLV RQEE AEDP ACIP IFWV SKWV DYSD KYGL GYQL CDNS VGVL FNDS TRLI LYND GDSL QYIE RDGT ESYL TVSS HPNS LMKK ITLL KYFR NYMS EHLL KAGA NITP REGD ELAR LPYL RTWF RTRS AIIL HLSN GSVQ INFF QDHT KLIL CPLM AAVT YIDE KRDF RTYR LSLL EEYG CCKE LASR LRYA RTMV DKLL SSRS ASNR LKAS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PLK; STPK13; PLK1 |
Positive Sample: | HT-29,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Midbody, Nucleus, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle. |
Calculated MW: | 68kDa |
Observed MW: | 62kDa |
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
Purification Method: | Affinity purification |
Gene ID: | 5347 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |