The Plexin B2 Polyclonal Antibody (CAB10069) is a valuable tool for researchers studying Plexin B2, a cell surface receptor involved in diverse biological processes such as cell migration, axon guidance, and angiogenesis. This antibody, produced in rabbits, exhibits high specificity for Plexin B2 in human samples and has been validated for use in Western blotting applications.Plexin B2 is a transmembrane protein that plays a crucial role in mediating cellular interactions and signal transduction pathways. Its involvement in various physiological and pathological processes, including cancer metastasis and neuronal development, makes it a promising target for research in cancer biology, neuroscience, and vascular biology.
By utilizing the Plexin B2 Polyclonal Antibody, researchers can accurately detect and study the expression and function of Plexin B2 in different cell types and tissues. This antibody's specificity and reliability make it an essential tool for investigating the molecular mechanisms underlying Plexin B2-mediated signaling pathways and their potential implications in disease development and progression.
Product Name:
PLXNB2 Rabbit Polyclonal Antibody
SKU:
CAB10069
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1080-1200 of human PLXNB2 (NP_036533.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
205kDa
Observed MW:
80kDa
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).
Purification Method:
Affinity purification
Gene ID:
23654
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PLXNB2 antibody (CAB10069) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
