The Plekhg4 Polyclonal Antibody (CAB16112) is a valuable tool for researchers studying Plekhg4, a protein involved in cell signaling and regulation. Raised in rabbits, this antibody is highly specific to human Plekhg4 and is validated for use in Western blot applications. By binding to the Plekhg4 protein, this antibody facilitates the detection and analysis of Plekhg4 in various cell types, making it an essential component for studies in signal transduction pathways and cellular function.Plekhg4, also known as a Ras GTPase-activating protein, plays a crucial role in regulating cellular processes such as cell growth, proliferation, and differentiation.
Its involvement in signaling cascades makes it a target of interest in research related to cancer, developmental biology, and neuroscience. By understanding the function of Plekhg4, researchers can uncover insights into disease mechanisms and potential therapeutic targets.Overall, the Plekhg4 Polyclonal Antibody (CAB16112) is a valuable tool for researchers seeking to explore the role of Plekhg4 in cellular processes and disease pathology, providing a key resource for advancing scientific knowledge and developing new therapeutic strategies.
Product Name:
PLEKHG4 Rabbit Polyclonal Antibody
SKU:
CAB16112
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 710-1010 of human PLEKHG4 (NP_001123199.1).
The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
25894
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat testis, using PLEKHG4 Rabbit pAb (CAB16112) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
