The Plek2 Polyclonal Antibody (CAB17682) is a valuable tool for researchers studying Plek2, a protein involved in various cellular processes, including cell signaling and cytoskeletal organization. This antibody, produced in rabbits, exhibits high specificity for Plek2 in human samples and is optimized for use in Western blot applications.Plek2, also known as Pleckstrin-2, plays a critical role in cell migration, adhesion, and intracellular signaling pathways. Its involvement in these processes makes it a promising target for research in cell biology and cancer biology. By utilizing the Plek2 Polyclonal Antibody, researchers can detect and analyze Plek2 protein levels in different cell types, providing valuable insights into its function and potential therapeutic applications.
Understanding the role of Plek2 in cellular physiology and disease pathogenesis is essential for developing targeted therapies for conditions such as cancer, cardiovascular diseases, and neurological disorders. The Plek2 Polyclonal Antibody offers researchers a reliable tool for investigating Plek2 functions and pathways, facilitating advancements in biomedical research and drug development.
Product Name:
PLEK2 Rabbit Polyclonal Antibody
SKU:
CAB17682
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PLEK2 (NP_057529.1).
The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease.
Purification Method:
Affinity purification
Gene ID:
26499
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLEK2 Rabbit pAb (CAB17682) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
