The Pleckstrin Polyclonal Antibody (CAB6305) is a valuable tool for researchers studying the pleckstrin protein, a key player in intracellular signaling pathways. This antibody, derived from rabbit serum, exhibits high specificity and sensitivity towards human pleckstrin, making it ideal for use in Western blotting and immunohistochemistry applications.Pleckstrin is involved in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of pleckstrin has been linked to various diseases, such as cancer and neurological disorders, highlighting the importance of studying its function and regulation.
By using the Pleckstrin Polyclonal Antibody, researchers can accurately detect and analyze pleckstrin expression in different cell types and tissues, providing valuable insights into its role in health and disease. This antibody is a valuable tool for advancing research in cell biology, cancer biology, and drug discovery.
Product Name:
PLEK Rabbit Polyclonal Antibody
SKU:
CAB6305
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human PLEK (NP_002655.2).
Enables phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; actin cytoskeleton organization; and positive regulation of supramolecular fiber organization. Located in cytoplasm and ruffle membrane.
Purification Method:
Affinity purification
Gene ID:
5341
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PLEK antibody (CAB6305) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
