The PLD3 Polyclonal Antibody (CAB18438) is a valuable tool for researchers studying the PLD3 protein, which is involved in the regulation of immune responses and cellular processes. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By binding to the PLD3 protein, this antibody enables the detection and analysis of PLD3 in various cell types, making it ideal for studies in immunology, neurology, and related fields.PLD3 is a phospholipase enzyme that plays a crucial role in lipid metabolism and the functioning of cellular membranes.
Dysregulation of PLD3 has been implicated in various diseases, including neurodegenerative disorders and metabolic conditions. By studying the function of PLD3, researchers can gain insights into the underlying mechanisms of these diseases and potentially develop targeted therapies.Overall, the PLD3 Polyclonal Antibody is a reliable tool for investigating the role of PLD3 in cellular processes and disease pathogenesis, providing valuable information for the development of novel treatment strategies.
Product Name:
PLD3 Rabbit Polyclonal Antibody
SKU:
CAB18438
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 279-490 of human PLD3 (NP_001026866).
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23646
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLD3 Rabbit pAb (CAB18438) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
