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PLD1 Polyclonal Antibody

SKU:
CAB24528
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
$155 - $431
Frequently bought together:

Description

PLD1 Polyclonal Antibody (CAB24528)

The PLD1 Polyclonal Antibody is a valuable tool for researchers studying phospholipase D1 (PLD1), a critical enzyme involved in lipid signaling pathways. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the PLD1 protein, this antibody allows for the detection and analysis of PLD1 expression in various cell types, making it ideal for investigations in cell signaling, lipid metabolism, and cancer research.

PLD1 is known to play a key role in various cellular processes, including cell growth, membrane trafficking, and cytoskeletal organization. Dysregulation of PLD1 activity has been implicated in diseases such as cancer, neurodegenerative disorders, and metabolic conditions. By studying the function of PLD1 with this antibody, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.

Product Name:PLD1 Polyclonal Antibody
Product Code:CAB24528
Reactivity:Mouse
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse
Tested Applications:IF/ICC, ELISA
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Cellular Location:Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Late endosome membrane, Lipid-anchor, perinuclear region

This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 940-1074 of human PLD1 (NP_002653.1).
Sequence:VMDGK EYQAG RFARG LRLQC FRVVL GYLDD PSEDI QDPVS DKFFK EVWVS TAARN ATIYD KVFRC LPNDE VHNLI QLRDF INKPV LAKED PIRAE EELKK IRGFL VQFPF YFLSE ESLLP SVGTK EAIVP MEVWT
Synonyms:PLD1, hPLD1, Phospholipase D1, Choline phosphatase 1, PLD 1, phospholipase D1
Calculated MW:68kDa/112kDa/119kDa/124kDa
Observed MW:Refer to figures

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