The PLC-L2 Polyclonal Antibody (CAB17660) is a valuable tool for researchers studying PLC-L2, a phospholipase C-like protein involved in cellular signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the PLC-L2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in areas such as signal transduction and cancer research.
PLC-L2 is known to play a crucial role in cell signaling processes by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate into inositol 1,4,5-trisphosphate and diacylglycerol. Its involvement in intracellular signaling cascades makes it a key target for research on cell growth, differentiation, and oncogenesis. Understanding the function of PLC-L2 is essential for uncovering its potential role in various disease states and for identifying new therapeutic targets in these areas.
Product Name:
PLCL2 Rabbit Polyclonal Antibody
SKU:
CAB17660
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-300 of human PLCL2 (NP_055999.2).
Enables GABA receptor binding activity. Predicted to be involved in negative regulation of cold-induced thermogenesis and phosphatidylinositol-mediated signaling. Predicted to act upstream of or within several processes, including B cell activation; gamma-aminobutyric acid signaling pathway; and negative regulation of B cell receptor signaling pathway. Predicted to be located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
23228
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse skeletal muscle, using PLCL2 Rabbit pAb (CAB17660) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
