PLC gamma 2 (PLCG2) Rabbit Monoclonal Antibody (CAB5182)
- SKU:
- CAB5182
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PLC gamma 2 (PLCG2) Rabbit Monoclonal Antibody |
SKU: | CAB5182 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human PLC gamma 2 (PLC gamma 2 (PLCG2)) (P16885). |
Sequence: | RHFV LGTS AYFE SLVE LVSY YEKH SLYR KMRL RYPV TPEL LERY NMER DINS LYDV SRMY VDPS EINP SMPQ RTVK ALYD YKAK RSDE LSFC RGAL IHNV S |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | FCAS3; APLAID; PLC-IV; PLC-gamma-2; PLC gamma 2 (PLCG2) |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome, perinuclear region of cytoplasm, plasma membrane, ruffle membrane |
Calculated MW: | 148kDa |
Observed MW: | 150kDa |
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Purification Method: | Affinity purification |
Gene ID: | 5336 |
Clone Number: | ARC1176 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |