PLCB2 Rabbit Polyclonal Antibody (CAB8141)
- SKU:
- CAB8141
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PLCB2 Rabbit Polyclonal Antibody |
SKU: | CAB8141 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_004564.2). |
Sequence: | MSLL NPVL LPPK VKAY LSQG ERFI KWDD ETTV ASPV ILRV DPKG YYLY WTYQ SKEM EFLD ITSI RDTR FGKF AKMP KSQK LRDV FNMD FPDN SFLL KTLT VVSG PDMV DLTF HNFV SYKE NVGK AWAE DVLA LVKH PLTA NASR STFL DKIL VKLK MQLN SEGK IPVK NFFQ MFPA DRKR VEAA LSAC HLPK GKND AIN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PLC-beta-2; PLCB2 |
Positive Sample: | HEL,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, G-protein beta/gamma-subunit complex, Golgi apparatus, neuronal dense core vesicle, plasma membrane |
Calculated MW: | 134kDa |
Observed MW: | 140kDa |
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
Purification Method: | Affinity purification |
Gene ID: | 5330 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |