This PLCB2 Polyclonal Antibody (CAB8141) is specifically designed for research involving the PLCB2 protein, a key player in intracellular signaling pathways. The antibody is produced using rabbits and has been shown to exhibit high reactivity with human samples. Validated for use in Western blot applications, this antibody binds specifically to the PLCB2 protein, allowing for accurate detection and analysis in various cell types.PLCB2 is an essential enzyme involved in the regulation of cellular signaling, particularly in processes related to immune responses and cell growth. Dysregulation of PLCB2 has been implicated in various diseases, including cancer, autoimmune disorders, and neurological conditions.
By studying the role of PLCB2 in these contexts, researchers can gain valuable insights into disease mechanisms and potentially identify therapeutic targets.With its high specificity and sensitivity, the PLCB2 Polyclonal Antibody (CAB8141) is a valuable tool for researchers in immunology, cancer biology, and other related fields. By facilitating the detection and analysis of PLCB2, this antibody enables further exploration of the intricate signaling pathways involved in immune regulation and disease progression.
Product Name:
PLCB2 Rabbit Polyclonal Antibody
SKU:
CAB8141
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_004564.2).
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
Purification Method:
Affinity purification
Gene ID:
5330
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat lung, using PLCB2 antibody (CAB8141) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
