The PLCB1 Polyclonal Antibody (CAB1971) is a valuable tool for researchers studying the PLCB1 protein, a key player in intracellular signaling pathways. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the PLCB1 protein, this antibody allows for the detection and analysis of PLCB1 expression levels in various cell types, making it an essential tool for research in molecular biology and cell signaling.PLCB1 is a member of the phospholipase C family, involved in the generation of key signaling molecules like inositol trisphosphate and diacylglycerol.
Its role in signal transduction cascades makes it a crucial target for understanding cellular processes such as cell growth, differentiation, and metabolism. Research into PLCB1 function is essential for identifying potential therapeutic targets in diseases like cancer, diabetes, and cardiovascular disorders where dysregulated signaling pathways play a role in pathogenesis.By utilizing the PLCB1 Polyclonal Antibody in experiments, researchers can gain valuable insights into the function and regulation of PLCB1, paving the way for potential breakthroughs in drug development and treatment strategies targeting PLCB1-related pathways.
Product Name:
PLCB1 Rabbit Polyclonal Antibody
SKU:
CAB1971
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 917-1216 of human PLCB1 (NP_056007.1).
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23236
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells using PLCB1 Rabbit pAb(CAB1971) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
