LCP1 Rabbit Polyclonal Antibody (CAB5561)
- SKU:
- CAB5561
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | LCP1 Rabbit Polyclonal Antibody |
SKU: | CAB5561 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human L-Plastin/LCP1 (NP_002289.2). |
Sequence: | MARG SVSD EEMM ELRE AFAK VDTD GNGY ISFN ELND LFKA ACLP LPGY RVRE ITEN LMAT GDLD QDGR ISFD EFIK IFHG LKST DVAK TFRK AINK KEGI CAIG GTSE QSSV GTQH SYSE EEKY AFVN WINK ALEN DPDC RHVI PMNP NTND LFNA VGDG IVLC KMIN LSVP DTID ERTI NKKK LTPF TIQE NLNL ALNS ASAI GCHV VNIG AEDL KEGK PYLV LGLL WQVI KIGL FADI ELSR NEAL IALL REGE SLED LMKL SPEE LL |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN; L-Plastin/LCP1 |
Positive Sample: | Raji,K-562,DU145,Jurkat,Mouse thymus,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, ruffle membrane. |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
Purification Method: | Affinity purification |
Gene ID: | 3936 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |