KLKB1 Rabbit Polyclonal Antibody (CAB5318)
- SKU:
- CAB5318
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | KLKB1 Rabbit Polyclonal Antibody |
SKU: | CAB5318 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human KLKB1 (NP_000883.2). |
Sequence: | GCLT QLYE NAFF RGGD VASM YTPN AQYC QMRC TFHP RCLL FSFL PASS INDM EKRF GCFL KDSV TGTL PKVH RTGA VSGH SLKQ CGHQ ISAC HRDI YKGV DMRG VNFN VSKV SSVE ECQK RCTS NIRC QFFS YATQ TFHK AEYR NNCL LKYS PGGT PTAI KVLS NVES GFSL KPCA LSEI GCHM NIFQ HLAF SDVD VARV LTPD AFVC RTIC TYHP NCLF FTFY TNVW KIES QRNV CLLK TSES GTPS SSTP QENT ISGY SLLT CKRT LPEP CHSK IYPG V |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PKK; PPK; KLK3; PKKD; KLKB1 |
Positive Sample: | Mouse plasma |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 71kDa |
Observed MW: | 80kDa |
This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 3818 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |