Placental alkaline phosphatase (PLAP) Rabbit Monoclonal Antibody (CAB4304)
- SKU:
- CAB4304
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Placental alkaline phosphatase (PLAP) Rabbit Monoclonal Antibody |
SKU: | CAB4304 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Placental alkaline phosphatase (PLAP) (P05187). |
Sequence: | ALSK TYNV DKHV PDSG ATAT AYLC GVKG NFQT IGLS AAAR FNQC NTTR GNEV ISVM NRAK KAGK SVGV VTTT RVQH ASPA GTYA HTVN RNWY SDAD VPAS A |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:500 - 1:1000 |
Synonyms: | ALP; IAP; ALPI; PALP; PLAP; PLAP-1; Placental alkaline phosphatase (PLAP) |
Positive Sample: | PC-3 cells,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 58kDa |
Observed MW: | 70kDa |
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
Purification Method: | Affinity purification |
Gene ID: | 250 |
Clone Number: | ARC0961 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |