Placental alkaline phosphatase (PLAP) Polyclonal Antibody (CAB21424)
- SKU:
- CAB21424
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IP
Frequently bought together:
Description
Product Name: | Placental alkaline phosphatase (PLAP) Polyclonal Antibody |
SKU: | CAB21424 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-460 of human Placental alkaline phosphatase (PLAP) (NP_001623.3). |
Sequence: | LAKR QGAR YVWN RTEL MQAS LDPS VTHL MGLF EPGD MKYE IHRD STLD PSLM EMTE AALR LLSR NPRG FFLF VEGG RIDH GHHE SRAY RALT ETIM FDDA IERA GQLT SEED TLSL VTAD HSHV FSFG GYPL RGSS IFGL APGK ARDR KAYT VLLY GNGP GYVL KDGA RPDV TESE SGSP EYRQ QSAV PLDE ETHA GEDV A |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ALP; IAP; ALPI; PALP; PLAP; PLAP-1; Placental alkaline phosphatase (PLAP) |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 58kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
Purification Method: | Affinity purification |
Gene ID: | 250 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |