The PACO47086 Plac8 Polyclonal Antibody is a cutting-edge tool for scientists researching Plac8, a protein associated with tumor development and progression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Plac8 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in cancer biology and oncology research.Plac8, also known as Placenta-specific 8, is a key player in the regulation of cell proliferation and survival, with implications in tumorigenesis and metastasis. Its presence in cancer cells has been linked to poor prognosis and resistance to therapy, making it a promising target for therapeutic intervention.
Researchers studying Plac8 aim to uncover its role in tumor growth and progression, offering insights into potential treatment strategies for cancer patients.The PACO47086 Plac8 Polyclonal Antibody is a valuable asset for scientists investigating the molecular mechanisms underlying cancer development, with the potential to lead to breakthroughs in targeted therapies and personalized medicine. Its specificity and reliability make it a powerful tool for advancing our understanding of Plac8 biology in cancer research.
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO47086 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO47086 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO47086 at dilution of 1:100.
Synonyms:
Placenta-specific gene 8 protein (Protein C15), PLAC8
UniProt Protein Function:
PLAC8: Belongs to the cornifelin family.Chromosomal Location of Human Ortholog: 4q21.22Molecular Function: chromatin bindingBiological Process: brown fat cell differentiation; defense response to bacterium; negative regulation of apoptosis; negative regulation of multicellular organism growth; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to cold
