The PLAA Polyclonal Antibody (CAB4294) is a valuable tool for researchers studying the PLAA protein, which plays a crucial role in various cellular processes including vesicle trafficking, autophagy, and apoptosis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the PLAA protein, researchers can effectively detect and analyze its expression in different cell types, making it an ideal tool for investigations in cell biology and cancer research.
PLAA, also known as phospholipase A-2-activating protein, is involved in the regulation of lipid metabolism and membrane dynamics within cells. Dysregulation of PLAA has been linked to various diseases, suggesting its potential as a therapeutic target for conditions such as cancer, neurodegenerative disorders, and metabolic syndromes. Research on PLAA is essential for understanding its role in cellular function and for developing targeted therapies that can modulate its activity for therapeutic benefit.
Product Name:
PLAA Rabbit Polyclonal Antibody
SKU:
CAB4294
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 536-795 of human PLAA (NP_001026859.1).
Predicted to enable ubiquitin binding activity. Involved in cellular response to lipopolysaccharide; macroautophagy; and positive regulation of phospholipase A2 activity. Located in cytoplasm; extracellular exosome; and nucleus.
Purification Method:
Affinity purification
Gene ID:
9373
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PLAA antibody (CAB4294) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
