The PLA2R1 Polyclonal Antibody (CAB10068) is a valuable tool for researchers studying the PLA2R1 protein, which is involved in autoimmune diseases such as membranous nephropathy. This antibody, produced using rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the PLA2R1 protein, researchers can accurately detect and analyze its expression in various cell types, making it an excellent choice for studies in immunology and nephrology.
PLA2R1 is known for its role in mediating immune responses and maintaining kidney function, making it a key target for investigation in autoimmune kidney diseases such as membranous nephropathy. Understanding the function and regulation of PLA2R1 is essential for developing targeted therapies and diagnostic tools for these conditions. The PLA2R1 Polyclonal Antibody provides researchers with a reliable tool to advance their understanding of this important protein and its implications in autoimmune diseases.
Product Name:
PLA2R1 Rabbit Polyclonal Antibody
SKU:
CAB10068
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1 (NP_031392.3).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
169kDa
Observed MW:
180kDa
This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
22925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using PLA2R1 Rabbit pAb (CAB10068) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
