The PLA2G7 Polyclonal Antibody (CAB9796) is a valuable tool for research involving PLA2G7, a secreted phospholipase enzyme linked to various inflammatory and metabolic diseases. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot and immunohistochemistry applications. By binding to the PLA2G7 protein, researchers can accurately detect and analyze its expression levels in different biological samples, facilitating studies in lipid metabolism, cardiovascular diseases, and inflammation.
PLA2G7, also known as Lipoprotein-associated phospholipase A2, is a key enzyme involved in the hydrolysis of phospholipids in lipoproteins, leading to the generation of pro-inflammatory mediators. Its role in lipid metabolism and inflammation makes it a potential therapeutic target for conditions such as atherosclerosis, cardiovascular diseases, and inflammatory disorders. Studying the function of PLA2G7 is essential for developing targeted interventions that can modulate its activity and potentially treat associated diseases.
Product Name:
PLA2G7 Rabbit Polyclonal Antibody
SKU:
CAB9796
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 172-441 of human PLA2G7 (NP_005075.3).
The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat serum, using PLA2G7 Rabbit pAb (CAB9796) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
