The PLA2G6 Polyclonal Antibody (CAB9492) is a valuable tool for researchers studying the PLA2G6 protein, which is involved in various cellular processes including lipid metabolism and membrane homeostasis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot analysis.PLA2G6, also known as phospholipase A2 group VI, is a key enzyme involved in the hydrolysis of membrane phospholipids, playing a crucial role in the regulation of cell signaling and membrane dynamics.
Dysregulation of PLA2G6 has been linked to various pathological conditions such as neurodegenerative disorders and inflammatory diseases.By utilizing the PLA2G6 Polyclonal Antibody, researchers can gain valuable insights into the expression levels and localization of the PLA2G6 protein in different cell types and tissues. This antibody is a valuable tool for studies focused on lipid metabolism, membrane biology, and the role of PLA2G6 in disease pathogenesis.
Product Name:
PLA2G6 Rabbit Polyclonal Antibody
SKU:
CAB9492
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 151-250 of human PLA2G6 (NP_003551.2).
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.
Purification Method:
Affinity purification
Gene ID:
8398
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Rat brain, using PLA2G6 Rabbit pAb (CAB9492) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
