PLA2G3 Rabbit Polyclonal Antibody (CAB17696)
- SKU:
- CAB17696
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PLA2G3 Rabbit Polyclonal Antibody |
SKU: | CAB17696 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PLA2G3 (NP_056530.2). |
Sequence: | RLAR FLRL HSPP EVTN MLWE LLGT TCFK LAPP LDCV EGKN CSRD PRAI RVSA RHLR RLQQ RRHQ LQDK GTDE RQPW PSEP LRGP MSFY NQCL QLTQ AARR P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SPLA2III; sPLA2-III; GIII-SPLA2; PLA2G3 |
Positive Sample: | 293T,K-562,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | centriole, extracellular region, extracellular space, plasma membrane, recycling endosome |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease.
Purification Method: | Affinity purification |
Gene ID: | 50487 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |