The PLA2G3 Rabbit Polyclonal Antibody (CAB17696) is a valuable tool for researchers studying PLA2G3, an enzyme involved in lipid metabolism and inflammation. Raised in rabbits, this antibody is highly specific and reacts strongly with human samples, making it ideal for use in Western blot applications. By binding to the PLA2G3 protein, this antibody enables researchers to detect and analyze the enzyme in various cell types, providing insights into its role in cellular processes.PLA2G3, also known as phospholipase A2 group III, is a key player in lipid signaling pathways and has been implicated in various physiological and pathological processes, including inflammation, cancer, and cardiovascular diseases.
By understanding the functions and regulation of PLA2G3, researchers may uncover potential therapeutic targets for treating these conditions. The PLA2G3 Rabbit Polyclonal Antibody (CAB17696) offers a reliable tool for investigating the role of PLA2G3 in cellular pathways and disease mechanisms, aiding in the advancement of biomedical research.
Product Name:
PLA2G3 Rabbit Polyclonal Antibody
SKU:
CAB17696
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PLA2G3 (NP_056530.2).
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
50487
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLA2G3 Rabbit pAb (CAB17696) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
