The PLA2G2D Polyclonal Antibody (CAB7165) is a valuable tool for research related to PLA2G2D, a key enzyme involved in lipid metabolism and inflammatory processes. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it an excellent choice for Western blot experiments. By targeting the PLA2G2D protein, researchers can effectively study its expression and function in various biological samples, providing insights into its role in lipid signaling pathways and inflammatory responses.PLA2G2D, also known as phospholipase A2 group IID, is known to play a crucial role in lipid metabolism by catalyzing the hydrolysis of membrane phospholipids to release fatty acids and bioactive lipid mediators.
Dysregulation of PLA2G2D activity has been implicated in various inflammatory conditions, making it a potential target for drug development in the treatment of diseases like atherosclerosis, inflammatory bowel disease, and arthritis. By investigating the function of PLA2G2D using this antibody, researchers can advance our understanding of lipid metabolism and inflammation, paving the way for the development of novel therapeutic strategies.
Product Name:
PLA2G2D Rabbit Polyclonal Antibody
SKU:
CAB7165
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-145 of human PLA2G2D (NP_036532.1).
This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
26279
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLA2G2D Rabbit pAb (CAB7165) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 90s.
