The PLA2G12A Polyclonal Antibody (CAB15902) is a valuable tool for researchers studying PLA2G12A, a phospholipase enzyme involved in lipid metabolism and inflammatory processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By specifically binding to the PLA2G12A protein, researchers can detect and analyze its expression in various cell types, making it ideal for investigations in lipid biology, inflammation, and related diseases.
PLA2G12A, a member of the phospholipase A2 enzyme family, is known for its involvement in modulating immune responses and lipid signaling pathways. Its role in lipid metabolism and inflammation makes it a promising target for research in metabolic disorders, inflammatory diseases, and cancer. Understanding the function of PLA2G12A can provide insights into the mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting lipid metabolism and inflammation.
Product Name:
PLA2G12A Rabbit Polyclonal Antibody
SKU:
CAB15902
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLA2G12A (NP_110448.2).
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).
Purification Method:
Affinity purification
Gene ID:
81579
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PLA2G12A Rabbit pAb (CAB15902) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 150s.
