The PKNOX1 Polyclonal Antibody (CAB15301) is a valuable tool for researchers studying the PKNOX1 protein, which is involved in transcriptional regulation and embryonic development. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blotting.PKNOX1, also known as Prep1, is a transcription factor that plays a crucial role in cell differentiation and patterning during embryonic development. It is also implicated in regulating gene expression in various tissues, making it a key player in developmental biology and cancer research.
By targeting PKNOX1 with this antibody, researchers can analyze its expression levels and localization in different cell types, providing important insights into its function.Understanding the role of PKNOX1 in development and disease is essential for unraveling its potential as a therapeutic target in conditions such as cancer and congenital disorders. By using the PKNOX1 Polyclonal Antibody, researchers can further explore the mechanisms by which PKNOX1 influences gene expression and cellular differentiation, paving the way for novel therapeutic strategies.
Product Name:
PKNOX1 Rabbit Polyclonal Antibody
SKU:
CAB15301
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 322-436 of human PKNOX1 (NP_004562.2).
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in angiogenesis and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within camera-type eye development; hemopoiesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be part of chromatin.
Purification Method:
Affinity purification
Gene ID:
5316
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using PKNOX1 Rabbit pAb (CAB15301) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
